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cml cell lines kcl22 and kcl22-ir  (KinaSense LLC)
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KinaSense LLC cml cell lines kcl22 and kcl22-ir
Calculated LogP and anti-proliferation activities of alkynyl analogs
Cml Cell Lines Kcl22 And Kcl22 Ir, supplied by KinaSense LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cml cell lines kcl22 and kcl22-ir - by Bioz Stars, 2026-10
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Calculated LogP and anti-proliferation activities of alkynyl analogs

Journal: ChemMedChem

Article Title: Alkynylnicotinamide-based compounds as ABL1 inhibitors with potent activities against drug-resistant CML harboring ABL1(T315I) mutant kinase.

doi: 10.1002/cmdc.201700829

Figure Lengend Snippet: Calculated LogP and anti-proliferation activities of alkynyl analogs

Article Snippet: Evaluation of compounds activity against ABL1 and ABL1(T315I) inside CML cell lines KCL22 and KCL22-IR (by KinaSense, West Lafayette, IN, USA).

Techniques:

Inhibition of cellular ABL1 activity by imatinib, ponatinib and HSN compounds

Journal: ChemMedChem

Article Title: Alkynylnicotinamide-based compounds as ABL1 inhibitors with potent activities against drug-resistant CML harboring ABL1(T315I) mutant kinase.

doi: 10.1002/cmdc.201700829

Figure Lengend Snippet: Inhibition of cellular ABL1 activity by imatinib, ponatinib and HSN compounds

Article Snippet: Evaluation of compounds activity against ABL1 and ABL1(T315I) inside CML cell lines KCL22 and KCL22-IR (by KinaSense, West Lafayette, IN, USA).

Techniques: Inhibition, Activity Assay